COVID-19 induced ARDS: immunopathology and therapeutics

The coronavirus disease-2019 (COVID-19) pandemic is a significant threat in the modern era. Clinical studies show that most common symptom of severe COVID-19 viral pneumonia-induced acute respiratory distress syndrome (ARDS). underlying mechanisms by which disease syndrome-coronavirus-2 (SARS-CoV-2) results ARDS and how certain host factors confer an increased risk developing remain unknown. Therefore, identifying distinctive features this fatal therapeutic approaches to COVID-19-induced remains immediate need serve as basis for best practice models standardized treatment. This review article aims comprehensively discuss immunopathology provides overview precise role both innate adaptive immune system, with emphasis on current treatment strategies being tested patients. knowledge will supposedly help revealing further mechanistic insights into understanding ARDS.